MyBioSource.com's Jagged1 antibody (PE) is a Hamster monoclonal antibody. The Jagged1 antibody (PE) was generated using AGS, AHD, CD339, JAG1, and Jagged 1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Armenian Hamster monoclonal Jagged1 antibody (PE)
This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor, Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen